Crystallization Facility
Structure Gallery
Here we present some of the protein structures recently elucidated using crystals grown at our protein crystallization platform:
Structure of fungal tRNA ligase Trl1 with RNA reveals conserved substrate-binding principles
Koehler et al. (2025)
pdb entries: 8RBJ
Strand-Swapped SH3 Domain Dimer with Superoxide Dismutase Activity
Haege, Schwan et al. (2025)
pdb entries: 9GGO
Structural and mechanistic insights into activation of human RNA ligase RTCB by Archease.
Gerber et al. (2024)
pdb entries: 8BTT 8BTX 8ODO 8ODP
Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
Klein et al. (2024)
pdb entries: 8ONX
Structural basis for binding of Drosophila Smaug to the GPCR Smoothened and to the germline inducer Oskar.
Kubikova et al. (2023)
Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.
Soni et al. (2023)
Structural and functional characterization of the N-terminal acetyltransferase Naa50.
Weidenhausen et al. (2021)
Structural basis of Naa20 activity towards a canonical NatB substrate.
Layer et al. (2021)
pdb entries: 6ZMP
Nanobody-Mediated Neutralization Reveals an Achilles Heel for Norovirus.
Koromyslova et al. (2020)
pdb entries: 6XW4 6XW5 6XW6 6XW7
Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL.
Sloan et al. (2020)
pdb entries: 6RY3 6RYD 6RYI 6RYL
The Arabidopsis Nα-acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response.
Linster, Layer et al. (2020)
The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Zhang, Gese et al. (2020)
pdb entries: 6SR6
Structural Basis of Nanobodies Targeting the Prototype Norovirus.
Ruoff et al. (2019)
pdb entries: 6H6Y 6H6Z 6H70 6H71 6H72
Structural analysis of a replication protein encoded by a plasmid isolated from a multiple sclerosis patient.
Kilic et al. (2019)
pdb entries: 6H24
DENR–MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation.
Ahmed et al. (2018)
pdb entries: 5ONS
Atomic Structure of the Murine Norovirus Protruding Domain and Soluble CD300lf Receptor Complex.
Kilic et al. (2018)
pdb entries: 5OR7
Molecular Mechanism of J-Domain-Triggered ATP Hydrolysis by Hsp70 Chaperones.
Kityk et al. (2018)
pdb entries: 5NRO
Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Kater et al. (2017)
Structure of Naa15/Naa10 bound to HypK-THB.
Weyer et al. (2017)
9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Dodonova et al. (2017)
pdb entries: 5MU7
Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis.
Rodrigues et al. (2017)
pdb entries: 5LNS, 5LNT, 5LNU, 5LNV, 5LNW, 5LNR
Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex.
Weyer et al. (2017)
Nat Struct Mol Biol. 24 144-151
pdb entries: 5MB9
Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain.
Gumiero et al. (2016)
pdb entries: 5TKY
Structural analysis of bovine norovirus protruding domain.
Singh et al. (2016)
pdb entries: 5E6T
Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction.
Horn et al. (2015)
Plasmodium falciparum antioxidant protein reveals a novel mechanism for balancing turnover and inactivation of peroxiredoxins.
Staudacher et al. (2015)
Free Radic Biol Med. 85 228-236
pdb entries: 4D73
Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA-binding site.
Calvino et al. (2015)
pdb entries: 5AFF
Structure of the complete bacterial SRP Alu domain.
Kempf et al. (2014)
Nucleic Acids Res. 42 12284-12294
SRP RNA remodeling by SRP68 explains its role in protein translocation.
Grotwinkel et al. (2014)
pdb entries: 4P3F
Structural characterization of a eukaryotic chaperone--the ribosome-associated complex.
Leidig et al. (2013)
Nat. Struct. Mol. Biol. 20 23-28
Structure and dynamics of the ATP-bound open conformation of Hsp70 chaperones.
Kityk et al. (2012)
pdb entries: 4B9Q
Synchronizing nuclear import of ribosomal proteins with ribosome assembly.
Kressler et al. (2012)
Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex.
Stefer et al. (2011)
pdb entries: 3SJA, 3SJB, 3SJC, 3SJD